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Cat#: VRS-0124-YT5187
Lenti-SARS-CoV-2 S Pseudovirus [Luciferase]
SARS-CoV-2 spike pseudovirus is generated by co-transfection 293T cells with psPAX, pLenti-Luciferase and a plasmid encoding SARS-CoV-2 S. The supernatants were harvested at 64 hours post transfection. The supernatants are centrifuged to remove cell debris and passed through filter to get pseudovirus. The pseudovirus express SARS-CoV-2 spike protein on the surface, and also a luciferase reporter which can be used to evaluate the SARS-CoV-2 infection when co-culture with human ACE2-overexpressed pseudohost. Pseudoviruses are useful virological tools because of their safety and versatility.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Severe Acute Respiratory Syndrome Coronavirus 2 |
| Virus Packaging Protein : | S (860 ng/mL) |
| Packaging System : | HIV-1 Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | Luciferase (Luciferase signal value can exceed 10^6 RLU (Relative Light Unit) at 48-72 hours post transfection with hACE2-293T cells.) |
| Titer : | 1x 1010 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 1 year from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | An outbreak of a novel coronavirus disease (COVID-19; previously known as 2019-nCoV) was reported since last December, 2019. Now COVID-19 is an emerging, rapidly evolving situation, and has become a pandemic.SARS-CoV-2 consists of four structural proteins, including S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins. As an important envelope protein, S protein is identified as the protein responsible for virus entry into human cells, and S protein is the major target for anti-SARS-CoV-2 therapeutics discovery. |
| Alternative Names : | SARS-CoV-2, 2019nCoV, COVID-19, S, Spike, Pseudovirus, Spike Pseudovirus, S Pseudovirus, SARS-CoV-2 Spike Pseudovirus, SARS-CoV-2 S Pseudovirus, COVID-19 Spike Pseudovirus, COVID-19 S Pseudovirus |
| Gene ID : | 43740568 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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