Anti-Hepatitis Virus Drug Discovery Products

Hepatitis viruses consist of a group of viruses that primarily target the liver, leading to liver disease. These viruses are classified into distinct types, each belonging to unique virus genera and families. Each type of hepatitis virus causes a different form of hepatitis and has its own specific characteristics.

• Hepatitis A virus (HAV) is a leading cause of hepatitis that has attracted much attention from the medical and scientific communities.
• Hepatitis B virus (HBV) is closely linked to the development of liver cancer, particularly hepatocellular carcinoma (HCC). It is estimated that approximately 80% of liver cancer cases worldwide are attributed to chronic HBV infection.
• Hepatitis C virus (HCV) infection is connected to severe liver damage, encompassing acute and chronic hepatitis, cirrhosis, and liver cancer.
• Hepatitis D virus (HDV) is considered a satellite virus that requires the presence of HBV for replication and infection. HDV can lead to severe liver damage, and the disease it causes is challenging to treat, often necessitating treatment for the underlying hepatitis B infection.
• Hepatitis E virus (HEV) typically manifests as a self-limiting illness but can be highly perilous for pregnant women.

The genomes of hepatitis viruses display varying structures and sizes. For instance, HAV and HEV possess single-stranded RNA genomes, whereas HBV has a partially double-stranded DNA genome. HCV has a single-stranded RNA genome with a high mutation rate, enabling it to evade the immune system. To facilitate researchers' understanding of these viruses and the development of more effective prevention and treatment strategies, our laboratory is committed to providing a variety of highly specific and sensitive anti-hepatitis virus antibodies.