Anti-EBOV Drug Discovery Products

Ebola virus (EBOV), also known as Ebola hemorrhagic fever virus, is a member of the Filoviridae family and the genus Ebolavirus. Ebola outbreaks are sporadic and primarily occur in Central and West Africa. This virus contains five different species: Zaire EBOV, Sudan EBOV, Taï Forest EBOV, Bundibugyo EBOV, and Reston EBOV. EBOV can cause severe hemorrhaging and multiple organ failure in humans. EBOV has a high mortality rate and has caused numerous outbreaks in recent years, sparking research into effective vaccines and antiviral measures.

The virion is a filamentous, non-enveloped virus with a diameter of approximately 80 nm. The genome is a single-stranded RNA with approximately 18kb in length. A single open reading frame encodes for the structural proteins (glycoprotein, nucleoprotein, matrix protein VP40 and VP24) and non-structural proteins (VP30, VP35, and L polymerase), respectively. The GP protein is involved in attachment and entry into host cells.

Creative Biolabs offers a wide range of antibodies and research tools for Ebola virus research, enabling researchers to detect viral proteins and investigate host-pathogen interactions. Please find the products below that meet your experimental requirements.