Anti-PV Drug Discovery Products

Poliovirus (PV), also known as the causative agent of Poliomyelitis, belongs to the Picornaviridae family and Enterovirus genus. This virus contains three serotypes (PV1, PV2, and PV3) and has historically plagued populations worldwide, causing the debilitating polio disease. Humans are the primary hosts, and transmission occurs through the fecal-oral route, making sanitation critical in preventing its spread. While poliovirus primarily targets the nervous system, leading to paralysis, advancements in medical science have paved the way for effective vaccines and antiviral measures. The poliovirus genome is a single-stranded RNA (ssRNA) molecule. The genome is approximately 7.4kb in length and contains a single open reading frame (ORF) that is divided into three regions: P1, P2, and P3. The P1 region encodes for the structural proteins of the virus, including the capsid protein (VP1-4) and the viral protein (VPg). The VP1-4 proteins form the icosahedral capsid of the virus, which protects the viral genome and is responsible for attachment and entry into host cells. VPg is a protein that is covalently linked to the 5' end of the genome and is involved in viral replication. Our lab provides a series of anti-Poliovirus antibody products for many applications.

If you're looking for an anti-Poliovirus antibody that will provide you with reliable and sensitive results, please contact our lab.