Anti-PUUV Drug Discovery Products

Puumala virus (PUUV), a member of the Orthohantavirus genus, causes a disease called nephropathia epidemica. The disease is characterized by fever, headache, back pain, and malaise, followed by oliguria or no urination, dark urine, and tea-colored urine. While PUUV primarily targets the kidneys, it can also affect the circulatory and respiratory systems. Puumala virus is primarily found in Europe, particularly in Scandinavia, Central Europe, and Russia.

The PUUV virion is pleomorphic in shape and enveloped with a diameter ranging from 80-120 nm. The genome of PUUV is a tripartite, single-stranded RNA (ssRNA) with approximately 12kb in length. The three RNA segments are designated large (L), medium (M), and small (S) based on their size. The L segment encodes the viral RNA-dependent RNA polymerase (RdRp), while the M segment encodes the two surface glycoproteins (Gn and Gc) involved in host cell entry. The S segment encodes the nucleocapsid (NP) and the phosphoprotein (P). At Creative Biolabs, we provide anti-PUUV antibody products for researchers studying PUUV and related diseases. Our products are designed to support virology research in deep.