Anti-Avian HEV Drug Discovery Products

Avian Hepatitis E virus (Avian HEV) is a member of Hepeviridae family. Avian HEV primarily infects the liver of avian species, causing hepatitis and other related diseases. Avian HEV has been detected in various avian species including chickens, ducks, geese, and turkeys. The viral genome is +ss RNA with 7.2 kb in length. The genome encodes a single ORF that is divided into three regions. ORF1 encodes the non-structural proteins involved in viral replication. ORF2 encodes the capsid protein (VP1) that forms the icosahedral viral capsid and mediates attachment and entry into host cells. ORF3 encodes the viral protein X (VPX) that mediates virus release from host cells.

There are four genotypes of Avian HEV. Genotype 1 is mainly found in humans and is responsible for human hepatitis E cases while Genotype 2 is mainly found in avian species and is responsible for avian hepatitis E cases. Genotype 3 and 4 are found in both humans and avian species.

Currently, vaccines have been developed for some genotypes of Avian HEV. At Creative Biolabs, we provide various anti-Avian HEV antibody products for researchers to support their research on Avian HEV and related diseases.

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