Anti-IBV Drug Discovery Products

Avian Infectious Bronchitis Virus (IBV) primarily infects chickens and other poultry species. It belongs to the genus Gammacoronavirus of the family Coronaviridae. The virus causes a highly contagious respiratory disease in chickens that can lead to severe economic losses in the poultry industry. IBV is typically transmitted through infected chickens or respiratory secretions. Infected chickens may show respiratory disease, decreased egg production, and other clinical symptoms. Vaccines are available to protect chickens from infection and to prevent IBV infection in poultry populations.

The IBV is an enveloped virus with a positive-sense, single-stranded RNA genome. The genomes are organized as 5'UTR-1a/1ab-S-3a-3b-E-M-5a-5b-N-3' UTR. It consists of several structural proteins including the spike (S), envelope (E), membrane (M), and nucleocapsid protein (N). Among them, the S protein consists of S1 and S2 domains, forming the peplomer projections on the surface of the virus and mediating attachment and entry into host cells. The ORF1a and 1b regions encode for the non-structural proteins such as RdRp.

At Creative Biolabs, we provide various anti-IBV drug discovery for researchers. With our comprehensive understanding of the IBV and our expertise in antibody and probe development, Creative Biolabs is committed to providing valuable tools for researchers to advance their studies on Avian Infectious Bronchitis Virus.