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Cat#: VRS-0124-YT5278
Lenti-JUNV GP Pseudovirus [GFP, VSV Packaging System]
The 293T cells expressing JUNV GPC proteins were infected with VSVΔG* which encodes the GFP gene. After 24 h the infected cell supernatants were collected and the pseudotyped viruses were purified by centrifugation through sucrose density gradients. The produced pseudoviruses carry JUUV GPC proteins, which is a powerful tool for Arenavirus vaccine development and entry inhibitor research.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Junin Virus |
| Virus Packaging Protein : | GP |
| Packaging System : | VSV Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | GFP |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Junin virus, also known as Argentine hemorrhagic fever (AHF), is a viral hemorrhagic fever caused by an infection with the Junin virus. It is typically transmitted to humans through contact with infected rodents. The glycoprotein of Junin virus is a viral protein that plays a crucial role in the entry of the virus into host cells and the initiation of infection. The glycoprotein is composed of two subunits, GP1 and GP2, which are generated by proteolytic cleavage of a precursor glycoprotein. GP1 is responsible for receptor binding, whereas GP2 is involved in membrane fusion. |
| Alternative Names : | Junin virus; GPC Pseudovirus; GPC; JUNV |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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