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Cat#: VRS-0124-YT5280
Lenti-JUNV GP Pseudovirus [EGFP, MLV Packaging System]
Lenti-JUUV GP Pseudovirus is produced by transfecting 293T cells with MLV gag/pol, pQCXIX-EGFP, and an JUUV GP expression plasmid. Pseudovirus-containing supernatant was harvested 48 h following transfection. The supernatant was cleared of cell debris by centrifugation and filtered through a 0.45-μm-pore-size filter. The produced pseudoviruses carry Arenavirus GP, which is applied for studying mechanism of virus entry, antiviral mechanism and screening antivirus inhibitor.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Junin Virus |
| Virus Packaging Protein : | GP |
| Packaging System : | MLV Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | EGFP |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Junin virus, also known as Argentine hemorrhagic fever (AHF), is a viral hemorrhagic fever caused by an infection with the Junin virus. It is typically transmitted to humans through contact with infected rodents. The glycoprotein of Junin virus is a viral protein that plays a crucial role in the entry of the virus into host cells and the initiation of infection. The glycoprotein is composed of two subunits, GP1 and GP2, which are generated by proteolytic cleavage of a precursor glycoprotein. GP1 is responsible for receptor binding, whereas GP2 is involved in membrane fusion. |
| Alternative Names : | Junin virus; GPC Pseudovirus; GPC; JUNV |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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