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Cat#: VRS-0124-YT5285
Lenti-CCHFV GP Pseudovirus [Luciferase, VSV Packaging System]
The 293T cells expressing CCHFV GP were infected with VSVΔG* bearing a luciferase gene. After 24 h the infected cell supernatants were collected and the pseudotyped viruses were purified by centrifugation through sucrose density gradients. The produced pseudoviruses carry CCHFV GP, which is a powerful tool for vaccine development and entry inhibitor research.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Crimean-Congo Hemorrhagic Fever Virus |
| Virus Packaging Protein : | GP |
| Packaging System : | VSV Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | Luciferase |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Crimean-Congo hemorrhagic fever virus (CCHFV) is a member of the Bunyaviridae family and Nairovirus genus. The viral genome consists of 3 RNA segments of 12 kb (L), 6.8 kb (M), and 3 kb (S). The L segment is 12164 nucleotides which bind to a promoter on each encapsidated segment, and transcribes the mRNA. The S segment of nairoviruses encodes only a large N protein and has no known nonstructural protein coding information. The M segment of the nairovirus seems to encode only G2 and G1. CCHF is the most widespread tickborne viral infection worldwide: it has been reported in many regions of Africa, the Middle East, and Asia. |
| Alternative Names : | CCHFV GP Pseudovirus; GP; CCFHV_sMgp1; CCHFV |
| Gene ID : | 2943074 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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