Anti-AdV Drug Discovery Products

Adenovirus (AdV) is a member of the Adenoviridae family. It can infect humans, animals, and insects. It is a common cause of respiratory, gastrointestinal, and ocular infections in humans. Vaccines have been developed to prevent some adenovirus serotypes, but treatment options are limited.

AdV is a non-enveloped virus with a diameter of approximately 70-90 nm. The genome is a double-stranded DNA (dsDNA) with approximately 35kb in length. It contains multiple open reading frames (ORFs), which are divided into early (E1-E4) and late (L1-L5) regions based on their expression during the viral replication cycle.

The E region genes encode proteins involved in transcription regulation, DNA replication, and host cell responses to infection. The L region genes encode structural proteins including the hexon, penton, fiber, and minor capsid proteins. These proteins form the icosahedral capsid, which protects the viral genome and is responsible for viral attachment and entry into host cells.

At Creative Biolabs, we provide anti-AdV antibody and probe products for researchers working in the field of AdV biology.