Lenti-HCV E2 Pseudovirus [GFP, VSV Packaging System]

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Cat#: VRS-0124-YT5269

Lenti-HCV E2 Pseudovirus [GFP, VSV Packaging System]

The CHO cell lines expressing HCV E2 envelope proteins were infected with VSVΔG* which encodes the GFP gene instead of the glycoprotein gene. After 16 h the infected cell supernatants were collected and the pseudotyped viruses were purified by centrifugation through sucrose density gradients. The produced pseudoviruses carry HCV E2 proteins, which is a powerful tool for HCV envelope protein function research.

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  • Product Summary
  • Packaging, Storage & Formulations
  • Target Details

Product Summary

Type : Pseudovirus
Virus Name : Hepatitis C Virus
Virus Packaging Protein : E2
Packaging System : VSV Packaging System
Packaging Cell : CHO cell lines
Reporter Gene : GFP
Titer : >1x 108 virus copies/mL
Application Notes : The pseudovirus can be usd for the following applications:
1. Antibody neutralization assay, Serum neutralization assay.
2. As virus standard alternative in diagnostic assay or others.
3. Drug screening including vaccine development, viral entry inhibitor development.
4. As a safe virology tool to discover the virus entry mechanisms.

Packaging, Storage & Formulations

Form : Liquid
Storage : Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles.
Shipping : Dry ice
Note : The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus.

Target Details

Introduction : Hepatitis C virus (HCV) is the most important causative agent of posttransfusion and sporadic non-A non-B hepatitis, infecting more than 200 million people worldwide. HCV infection becomes chronic in most cases and may eventually result in hepatitis, liver cirrhosis, and hepatocellular carcinoma. The HCV genome encodes two envelope glycoproteins (E1 and E2), which are thought to be responsible for receptor binding and membrane fusion resulting in virus penetration.
Alternative Names : HCV E2; Envelope glycoprotein; Structural polyprotein

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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