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Cat#: VRS-0124-YT1102
ViroProbe™ Human Immunodeficiency Virus 1/Clade B Gag-Pol Probe-Sense
Creative Biolabs provides probes that can amplify target-specific signals and detect RNA target expression with high sensitivity and specificity. The probes can be designed to target the sense or antisense sequences. Standard probes for RNA detection are in antisense. Sense probe is reverse complement to the corresponding antisense probe. This HIV1/Clade B Gag-Pol Sense probe is designed to target gag and pol RNA of Human immunodeficiency virus 1 (HIV)/Clade B and is specific for the detection of HIV1/Clade B in cellular and tissue environments. The probe can be used in situ hybridization. The probe is for HIV infection research use only and is not approved for use in humans or in clinical diagnosis.
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- Product Summary
- Product Specification
- Target Details
Product Summary
| Product Type : | RNA Probe |
| Probe Type : | Sense Probe |
| Specificity : | Human immunodeficiency virus 1 |
| No. of Pairs : | 40 |
| Application : | ISH |
| Application Notes : | This probe is sufficient for staining 20 sections, each with an area of approximately 20 mm x 20 mm. |
| Sample Source : | Formalin-fixed, paraffin-embedded (FFPE) tissue, fresh‑frozen tissue, fixed‑frozen tissue, and cultured cells. |
| Assay Type : | Chromogenic assay; Fluorescent assay |
Product Specification
| Size : | 3 mL |
| Form : | Liquid |
| Concentration : | 1× concentration |
| Storage : | Store at 2-8°C for long term. Refer to the COA file for specifics. |
| Shelf Life : | Stable for two year after receipt when stored as recommended. |
Target Details
| Full Name : | Gag polyprotein; DNA polymerase |
| Accession number : | AF324493.2 |
| Target Region : | 854-3940 |
| Introduction : | Human immunodeficiency virus (HIV) is a virus that attacks the body's immune system and causes acquired immunodeficiency syndrome (AIDS). Two types of HIV have been characterized: HIV-1 and HIV-2. HIV-1 is more virulent and more infective than HIV-2, and is the cause of the majority of HIV infections globally. HIV-1 is further classified into four groups; M, N, O and P. Of these, group M is the most widespread worldwide. Group M is divided into nine distinct clades; A, B, C, D, F, G, H, J and K. Clade B is the most widespread HIV-1 variant. HIV-1 is a retrovirus, belonging to a group of heterogeneous, lipid-enveloped RNA viruses. Gag has demonstrated the ability to specifically recognize genomic RNA and both viral and host proteins as it traffics to the cell membrane. DNA polymerase (pol) integrates the DNA produced by reverse transcriptase into the host's genome. |
| Alternative Names : | Gag polyprotein; gag; HIV1 Pr55Gag; Human immunodeficiency virus 1; Nucleocapsid protein p7; DNA polymerase; pol; HIV1; HIV; subtype B; clade B |
| Virus Subtype : | Clade B |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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