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Cat#: VRS-0124-YT1142
ViroProbe™ Canine Herpesvirus 1 Base Probe, Sense
Creative Biolabs provides probes that can amplify target-specific signals and detect RNA target expression with high sensitivity and specificity. The Base specific probe is designed to detect the nucleotide difference in the single cell including splice variants, short/highly homologous RNA sequences, and point mutations. The probes can be designed to target the sense or antisense sequences. Standard probes for RNA detection are in antisense. Sense probe is reverse complement to the corresponding antisense probe. Canine Herpesvirus 1 Base Probe is specific for the detection of thymidine kinase+strand gene of Canine Herpesvirus 1 (CHV-1) in cellular and tissue environments. The probe can be used in situ hybridization. The probe is for CHV-1 infections research use only and is not approved for use in humans or in clinical diagnosis.
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- Product Summary
- Product Specification
- Target Details
Product Summary
Product Type : | RNA Probe |
Probe Type : | Sense Probe |
Specificity : | Canine herpesvirus |
Target : | Thymidine kinase +strand |
No. of Pairs : | 1 |
Application : | ISH |
Application Notes : | This probe is sufficient for staining 20 sections, each with an area of approximately 20 mm x 20 mm. |
Sample Source : | Formalin-fixed, paraffin-embedded (FFPE) tissue, fresh‑frozen tissue, fixed‑frozen tissue, and cultured cells. |
Assay Type : | Chromogenic assay |
Product Specification
Size : | 3 mL |
Form : | Liquid |
Storage : | Store at 2-8°C for long term. Refer to the COA file for specifics. |
Shelf Life : | Stable for two year after receipt when stored as recommended. |
Target Details
Full Name : | Thymidine kinase |
Accession number : | X75765.1 |
Introduction : | Canine herpesvirus (CHV), also named anid alphaherpesvirus 1 (CaHV-1), is an enveloped double stranded DNA virus in the family Herpesviridae. Thymidine kinase (TK) genes are virulence-related genes and are nonessential for viral replication. CHV infects only canids. CHV1 causes a variety of diseases in dogs and infected dogs remain latent carriers for life. CHV can cause a variety of symptoms, that adds to the difficulty in recognising this disease. CHV infection cause a rapidly progressive and fatal multisystemic disease (including fatal hemorrhagic disease) in neonatal puppies, while generally produces mild clinical signs in adult male dogs, limited to the respiratory or genital tract. |
Alternative Names : | Canine herpesvirus; CHV; anid alphaherpesvirus 1; CaHV-1; Thymidine kinase; TK |
Virus Subtype : | Canid alphaherpesvirus 1 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.