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Cat#: VRS-1223-YT4
ViroAb™ Mouse Anti-BRSV N Monoclonal Antibody (XJ0545)
This Mouse Monoclonal antibody is specific for N protein of Bovine respiratory syncytial virus (BRSV). The antibody can be used for applications: IHC, ELISA. The antibody is for Respiratory tract infection disease research use only and is not approved for use in humans or in clinical diagnosis.
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- Target Published Figures
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Pathology of BRSV pneumonia
Alveolar lumen filled with macrophages and syncytial cells having intracytoplasmic inclusion (arrow) (Left, 400x). H&E; granular apple green fluorescence in the epithelium cells and macrophages (Right, 400x).
- Product Overview
- Product Properties
- Packaging, Storage & Formulations
- Applications
Product Overview
| Target : | N |
| Specificity : | This antibody recognizes the 42kD nucleoprotein of RSV. |
| Clone : | XJ0545 |
| Host Species : | Mouse |
| Antibody Isotype : | IgG1 |
| Species Reactivity : | Bovine Respiratory Syncytial Virus |
Product Properties
| Immunogen : | Bovine RSV (strains 127, SNK and 9007), Human RSV (strains A2, Long, Randall and 8/60). |
| Purification : | Affinity chromatography purified |
| Concentration : | Lot specific |
Packaging, Storage & Formulations
| Form : | Liquid |
| Formulation : | PBS (pH 7.2) |
Applications
| Application : | IHC; ELISA |
| Application Notes : | The optimal working dilutions should be determined by the end user. |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Kamdi, Bhupesh, et al. "Immunofluorescence and molecular diagnosis of bovine respiratory syncytial virus and bovine parainfluenza virus in the naturally infected young cattle and buffaloes from India." Microbial pathogenesis 145 (2020): 104165.
Virology-
(Verified Customer)
I used this anti-BRSV N antibody in the detection of the BRSV in paraffin-embedded lung tissue sections by the immunohistochemistry assay. The results showed that this antibody had a good target specificity.
Dear sir,
We're interested in the product "VRS-1223-YT4". Can you provide an HRP-conjugated antibody?
Regards,
Caleb
Thank you for contacting us. Yes, We are able to conjugate the antibody to common analytically-detectable regents including HRP. Please don't hesitate to contact us if you need any further advice or information on other aspects.
Target Research Highlights
Pneumonia in bovines is a multifactorial disease manifestation leading to heavy economic losses. Infections of bovine respiratory syncytial virus (BRSV) is among the important contributing factors for the development of pneumonia in young animals. Out of 406 cases, twelve (2.95%) cases were positive for BRSV screened by reverse transcriptase polymerase chain reaction (RT-PCR) and direct immunofluorescence antibody test (d-FAT) in paraffin-embedded lung tissue sections. The BRSV antigen distribution was found to be in bronchiolar and alveolar epithelium and syncytial cells in the lung sections. RT-PCR amplicons of BRSV obtained were sequenced and their analysis showed homology with already available sequences in the NCBI database.
References
Kamdi, Bhupesh, et al. "Immunofluorescence and molecular diagnosis of bovine respiratory syncytial virus and bovine parainfluenza virus in the naturally infected young cattle and buffaloes from India." Microbial pathogenesis 145 (2020): 104165.
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