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Cat#: VRS-0224-YT1031
ViroAb™ Human Anti-MERS-CoV Spike Monoclonal Antibody (XS-0234), Fc Engineered
This Human Monoclonal antibody is specific for MERS-CoV Spike protein. The antibody can be used for applications: Block, Neut. The antibody is for Middle East Respiratory Syndromedisease research use only and is not approved for use in humans or in clinical diagnosis.
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- Product Overview
- Product Properties
- Packaging, Storage & Formulations
- Applications
Product Overview
| Target : | S |
| Target Specific Region : | S1 |
| Specificity : | This antibody specifically binds the amino acids 349-590 in the S1 domain of the MERS-CoV. |
| Clone : | XS-0234 |
| Host Species : | Human |
| Antibody Isotype : | IgG1(Fc Engineered), Kappa |
| Species Reactivity : | MERS-COV |
Product Properties
| Immunogen : | The original antibody was generated by isolating neutralizing antibodies from a non-immune human Ab-phage library using a novel panning strategy. |
| Purity : | >95% as determined by SDS-PAGE |
| Purification : | Protein A affinity chromatography |
| Concentration : | 1.0 mg/mL (lot specific) |
Packaging, Storage & Formulations
| Form : | Liquid |
| Formulation : | PBS, 0.02% Proclin 300 |
| Preservative : | 0.02% Proclin 300 |
| Storage : | Store at 4°C for short term. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Applications
| Application : | Neut |
| Application Notes : | This antibody was created using our proprietary engineered Fc domain containing key point mutations that abrogate binding to Fc gamma receptors. This antibody blocks the binding of MERS-CoV spike protein to DPP4 receptor by binding to the aa 349-590 in the S1 domain of the MERS-CoV. The optimal working dilutions should be determined by the end user. |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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