Documents
Cat#: VRH-21599F
pepFastX™ Mouse Anti-VACV WR D1R (ITLTNVVNISTIQES) Monoclonal Antibody (21599YF)
This mouse monoclonal antibody 21599YF is generated from premade hybridoma library, and specific for Vaccinia virus WR D1R (AA 48-62): ITLTNVVNISTIQES. For any additional requirments, please specify and submit an inquiry for assistance.
Made to Order Requirements
Your choose infomation:
CLEAR(Note: Please select the requirements to fit you project. If you have any other requirements, please specify. If no specific requirements, you don't need to select any button.)
- Target Published Figures
- Antibody Testing Data
- Product Overview
- Product Properties
- Applications
Product Overview
Target : | D1R |
Specificity : | VACV WR |
Clone : | 21599YF |
Host Species : | Mouse |
Antibody Isotype : | IgG |
Species Reactivity : | Vaccinia virus |
Product Properties
Immunogen : | Synthetic peptide corresponding to amino acid sequence: ITLTNVVNISTIQES. |
Epitope : | ITLTNVVNISTIQES |
Purity : | >95% |
Purification : | Protein A or G affinity chromatography |
Concentration : | Lot specific |
Applications
Application : | ELISA |
Application Notes : | The antibody is screened by ELISA using the synthetic peptide that corresponds to amino acids sequence (ITLTNVVNISTIQES) as the capture antigen. Additional applications have not been validated. It is recommended that the end users validate other applications and determine optimal concentrations/dilution under their experimental conditions. |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Role of metalloproteases in vaccinia virus epitope processing for transporter associated with antigen processing (TAP)-independent human leukocyte antigen (HLA)-B7 class I antigen presentation.
Virology-
(Verified Customer)
After a Google search, this is the only commercially available antibody product targeting VACV WR D1R. I'm looking forward to seeing the results.
Dear sir:
We're interested in antibody VRH-21599F. Please help us confirm which epitope is recognized by VRH-21599F?
Best wishes,
Sally
Thanks for contacting us.
The epitope of this antibody VRH-21599F is ITLTNVVNISTIQES. I hope this was helpful. Please let us know if you have any further questions.
Target Research Highlights
D1R is involved in mRNA synthesis, as an mRNA capping enzyme large subunit. Cytotoxic CD4+ T cells recognize D1R epitopes in association with HLA-DR1 Ags.
References
Mitra-Kaushik, Shibani, et al. "Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses." The Journal of Immunology 179.2 (2007): 1303-1312.