Lenti-NiV G/F Pseudovirus [Luciferase, VSV Packaging System]

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Cat#: VRS-0124-YT5203

Lenti-NiV G/F Pseudovirus [Luciferase, VSV Packaging System]

The 293T cells expressing NiV G and F proteins were infected with VSVΔG* which encodes the luciferase gene. After 24 h the infected cell supernatants were collected and the pseudotyped viruses were purified by centrifugation through sucrose density gradients. The produced pseudoviruses carry NiV G and F proteins, which is a powerful tool for vaccine development and entry inhibitor research.

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  • Product Summary
  • Packaging, Storage & Formulations
  • Target Details

Product Summary

Type : Pseudovirus
Virus Name : Nipah Virus
Virus Packaging Protein : G/F
Packaging System : VSV Packaging System
Packaging Cell : 293T
Reporter Gene : Luciferase
Titer : >1x 108 virus copies/mL
Application Notes : The pseudovirus can be usd for the following applications:
1. Antibody neutralization assay, Serum neutralization assay.
2. As virus standard alternative in diagnostic assay or others.
3. Drug screening including vaccine development, viral entry inhibitor development.
4. As a safe virology tool to discover the virus entry mechanisms.

Packaging, Storage & Formulations

Form : Liquid
Storage : Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles.
Shipping : Dry ice
Note : The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus.

Target Details

Introduction : Nipah virus (NiV) is a deadly pathogen, which is transmitted by bodily fluids from pteropid fruit bats and livestock to humans. It is a nonsegmented, single-stranded, negative-sense RNA virus belonging to the genus Henipavirus, family Paramyxoviridae. The NiV envelope contains two surface glycoproteins required for cellular entry: the attachment protein (NiV-G) and fusion protein (NiV-F). Niv-G allows for attachment of the virion to cellular receptors, whereas NiV-F mediates the direct union of the virus and cellular membranes.
Alternative Names : NiV G; GP; F; G/F; NiV; NiV G/F Pseudovirus
Gene ID : 920955;920954

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.


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