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Cat#: VRS-0124-YT5282
Lenti-Measles virus H/F Pseudovirus [Luciferase, VSV Packaging System]
The 293T cells expressing both H and F proteins of measles virus were infected with VSVΔG* bearing a luciferase gene. After 24 h the infected cell supernatants were collected and the pseudotyped viruses were purified by centrifugation through sucrose density gradients. The produced pseudoviruses carry measles virus H and F proteins, which is a powerful tool for neutralization antibody assay, vaccine development and entry inhibitor research.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Measles Virus |
| Virus Packaging Protein : | H and F proteins |
| Packaging System : | VSV Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | Luciferase |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Measles virus is a member of the genus Morbillivirus of the family Paramyxoviridea. It is an enveloped, non-segmented, single-stranded, negative-sense RNA virus. Measles virions are seen as pleomorphic spheres with a diameter of 100-250 nm on electron microscopy. Measles virus encodes at least eight structural proteins, which have letter names: F, C, H, L, M, N, P, and V. Of these proteins, H (hemagglutinin) has a role in the attachment of the virus to host cells, and F (fusion) is involved in the spread of the virus from one cell to another. |
| Alternative Names : | Measles virus H/F Pseudovirus; H/F; Hemagglutinin protein; Fusion protein; MeVgp5; MeVgp4; Measles virus |
| Gene ID : | 1489800;1489801 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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