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Cat#: VRS-0124-YT5283
Lenti-Lyssavirus GP Pseudovirus [Luciferase, VSV Packaging System]
The 293T cells expressing Lyssavirus GP were infected with VSVΔG* bearing a luciferase gene. After 24 h the infected cell supernatants were collected and the pseudotyped viruses were purified by centrifugation through sucrose density gradients. The produced pseudoviruses carry Lyssavirus GP, which is a powerful tool for neutralization antibody assay, vaccine development and entry inhibitor research.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Rabies Virus |
| Virus Packaging Protein : | GP |
| Packaging System : | VSV Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | Luciferase |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Lyssavirus is a genus of RNA viruses in the family Rhabdoviridae, order Mononegavirales. The genus Lyssavirus includes the rabies virus traditionally associated with that disease. Lyssavirions are enveloped, with bullet shaped geometries. These virions are about 75 nm wide and 180 nm long. Lyssavirions have helical symmetry, so their infectious particles are approximately cylindrical in shape. This is typical of plant-infecting viruses. Virions of human-infecting viruses more commonly have cubic symmetry and take shapes approximating regular polyhedra. The structure consists of a spiked outer envelope, a middle region consisting of matrix protein M, and an inner ribonucleocapsid complex region, consisting of the genome associated with other proteins. |
| Alternative Names : | Lyssavirus GP Pseudovirus; GP; RABVgp4; Lyssavirus |
| Gene ID : | 1489856 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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