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Cat#: VRS-0124-YT5296
Lenti-LCMV GP Pseudovirus [EGFP, MLV Packaging System]
Lenti-LCMV GP Pseudovirus is produced by transfecting 293T cells with MLV gag/pol, pQCXIX-EGFP, and an LCMV GP expression plasmid. Pseudovirus-containing supernatant was harvested 48 h following transfection. The supernatant was cleared of cell debris by centrifugation and filtered through a 0.45-μm-pore-size filter. The produced pseudoviruses carry LCMV GP, which is applied for studying mechanism of virus entry, antiviral mechanism and screening antivirus inhibitor.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Lymphocytic Choriomeningitis Virus |
| Virus Packaging Protein : | GP |
| Packaging System : | MLV Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | EGFP |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | The Lymphocytic Choriomeningitis Virus (LCMV) is a member of the Arenaviridae family and is associated with a disease called lymphocytic choriomeningitis. This virus was first discovered in 1933 when it was isolated from a patient with meningitis. LCMV is considered to be a zoonotic virus and primarily transmitted through the urine, saliva, and droppings of infected rodents. The virus typically causes a mild or asymptomatic illness in humans. However, in individuals with weakened immune systems or during pregnancy, LCMV infection can lead to more severe complications, including meningitis, encephalitis, and even fetal malformations or miscarriage. |
| Alternative Names : | Arenavirus GPC Pseudovirus; GPC; Lymphocytic Choriomeningitis Virus GPC Pseudovirus; LCMV |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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