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Cat#: VRS-0124-YT5293
Lenti-GTOV GP Pseudovirus [EGFP, MLV Packaging System]
Lenti-GTOV GP Pseudovirus is produced by transfecting 293T cells with MLV gag/pol, pQCXIX-EGFP, and an GTOV GP expression plasmid. Pseudovirus-containing supernatant was harvested 48 h following transfection. The supernatant was cleared of cell debris by centrifugation and filtered through a 0.45-μm-pore-size filter. The produced pseudoviruses carry GTOV GP, which is applied for studying mechanism of virus entry, antiviral mechanism and screening antivirus inhibitor.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
Type : | Pseudovirus |
Virus Name : | Guanarito Virus |
Virus Packaging Protein : | GP |
Packaging System : | MLV Packaging System |
Packaging Cell : | 293T |
Reporter Gene : | EGFP |
Titer : | >1x 108 virus copies/mL |
Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
Form : | Liquid |
Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
Shipping : | Dry ice |
Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
Introduction : | Guanarito virus (GTOV) belongs to the Arenaviridae family of viruses, which are responsible for causing severe hemorrhagic fevers in humans. The disease caused by GTOV is known as Venezuelan hemorrhagic fever (VHF). The virus is primarily transmitted to humans through contact with infected rodents. The envelope glycoproteins of GTOV play a crucial role in its lifecycle and pathogenicity. These glycoproteins, known as GP1 and GP2, are responsible for the virus entry into host cells and subsequent fusion with the cellular membrane. |
Alternative Names : | Guanarito virus GPC Pseudovirus; GPC; GTOV GPC Pseudoviru |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.