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Cat#: VRS-0124-YT5205
Lenti-FIV RD114 env Pseudovirus [GFP, pCMVΔR8.2]
Lenti-FIV RD114 env pseudovirus is produced by cotransfecting 293T cells with pcDNA3.1/Zeo(+) expression plasmid encoding RD114 protein, the transfer vector TRIP GFP or HPV-402, and the packaging plasmid CMVDR8.2. Pseudovirus-containing supernatant was harvested 48 h following transfection. The supernatant was cleared of cell debris by centrifugation and filtered through a 0.45-μm-pore-size filter.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Feline Immunodeficiency Virus |
| Virus Packaging Protein : | RD114 |
| Packaging System : | HIV-1 Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | GFP |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Feline immunodeficiency virus (FIV) is a Lentivirus that affects cats worldwide, with 2.5% to 4.4% of felines being infected. FIV differs taxonomically from two other feline retroviruses, feline leukemia virus and feline foamy virus, and is more closely related to human immunodeficiency virus. Within FIV, five subtypes have been identified based on nucleotide sequence differences coding for the viral envelope or polymerase. FIV is the only non-primate lentivirus to cause an AIDS-like syndrome, but FIV is not typically fatal for cats, as they can live relatively healthily as carriers and transmitters of the disease for many years. |
| Alternative Names : | FIV env; FIV RD114 env Pseudovirus; FIVgp5 |
| Gene ID : | 1489987 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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