Anti-NoV Drug Discovery Products

Norovirus (NoV), also known as Norwalk virus, belongs to the Caliciviridae family and Norovirus genus. Humans are the primary hosts. Similar to Poliovirus, NoV is also transmitted through the fecal-oral route, and it primarily targets the gastrointestinal tract, causing diarrhea and vomiting. The illness is usually self-limiting and does not require treatment other than rehydration. However, in immunocompromised individuals, the virus can lead to prolonged infections and even death. Therefore, it is important to continue to study NoV for a better understanding of its transmission, pathogenesis, and development of effective prevention and treatment strategies.

The virion is a small, non-enveloped virus with 30 nm in diameter. The genome is a single-stranded RNA (ssRNA) with 7.5kb in length. The three ORFs encode nonstructural proteins (NS1-7), VP1, and VP2, respectively. The structural proteins VP1 and VP2 proteins form the viral capsid. Uncovering the mysteries of the NoV provides a vital foundation for the development of effective treatment. At Creative Biolabs, we offer a wide range of anti-NoV antibody products and services to meet your needs.