Documents
Cat#: VRS-0124-YT5288
Lenti-Visna virus Env Pseudovirus [GFP, MLV Packaging System]
Lenti-Visna virus Env Pseudovirus is produced by cotransfecting 293T cells with pCgp (MuLV gag-pol), pMX-GFP, and the plasmids expressing visna virus Env proteins. Pseudovirus-containing supernatant was harvested 48 h following transfection. The supernatant was cleared of cell debris by centrifugation and filtered through a 0.45-μm-pore-size filter. The produced pseudoviruses carrying visna virus Env proteins is a powerful tool for studying mechanism of virus entry, antiviral mechanism and screening antivirus inhibitor.
Made to Order Requirements
Your choose infomation:
CLEAR(Note: Please select the requirements to fit you project. If you have any other requirements, please specify. If no specific requirements, you don't need to select any button.)
- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Visna/Maedi Virus |
| Virus Packaging Protein : | Env |
| Packaging System : | MLV Packaging System |
| Packaging Cell : | 293T |
| Reporter Gene : | GFP |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Visna virus from the genus Lentivirus and subfamily Orthoretrovirinae, is a "prototype" retrovirus that causes encephalitis and chronic pneumonitis in sheep. It is known as visna when found in the brain, and maedi when infecting the lungs. Lifelong, persistent infections in sheep occur in the lungs, lymph nodes, spleen, joints, central nervous system, and mammary glands. Visna virus particles are spheres approximately 100 nm in diameter. Virions consist of an icosahedral capsid surrounded by an envelope derived from the host plasma membrane. Inside the capsid are the nucleoprotein-genome complex and the reverse transcriptase and integrase enzymes. A crystal structure of the virion has not been obtained and the triangulation number of the icosahedron is unknown. |
| Alternative Names : | Visna virus Env Pseudovirus; Env; Envelope polyprotein |
| Gene ID : | 1490016 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
pepFastX™ Platform
If no antibody is available for your research, we recommend our novel pepFastX™ antibody discovery platform. The mAb products can be delivered within 2-3 months.
Learn more
We're here to help
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.
Contact tech support