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Lot Number
Creative Biolabs has been setting the standard in quality virology research reagents for over 10 years.
This Mouse Monoclonal antibody (XF0017) is specific for SARS-CoV / SARS-CoV-2 N protein. The antibody can be used for applications: WB, ICC/IF. The antibody is for Severe acute respiratory syndrome (SARS) disease research use only and is not approved for use in humans or in clinical diagnosis.
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Product Summary | |
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Product Category | Primary Antibody |
Target | N |
Host | Mouse |
Species Reactivity | SARS-CoV, SARS-CoV-2 |
Clonality | Monoclonal |
Application | WB, ICC, IF |
Product Details | |
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Specificity | This antibody reacts with NP protein of SARS-CoV and SARS-CoV-2. |
Clone | XF0017 |
Immunogen | The immunogen used to generate this antibody corresponds to SARS-CoV Nucleocapsid (121-422 a.a.). |
Isotype | IgG1 |
Conjugation | Unconjugated |
Antigen Details | |
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Full Name | Nucleocapsid Protein |
Introduction | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. |
Gene ID | 43740575 |
Alternative Names | Nucleocapsid protein, Nucleocapsid, Nucleoprotein, N, NP, Coronavirus NP, Coronavirus Nucleocapsid protein, Coronavirus Nucleocapsid, Coronavirus Nucleoprotein, Coronavirus N, SARS-CoV-2 NP, SARS-CoV-2 Nucleocapsid protein, SARS-CoV-2 Nucleocapsid, SARS-CoV-2 Nucleoprotein, SARS-CoV-2 N |
Related Disease | Severe acute respiratory syndrome (SARS)/COVID-19 |
Virus Details | |
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Virus Family | Coronaviridae |
Virus Species | SARS-CoV/SARS-CoV-2 |
Virus Classification | Positive-sense RNA Virus |
Packaging, Storage & Formulations | |
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Purification | Protein G purified |
Storage | Store at 4°C for short term (1-2 weeks). Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics. |
Buffer | PBS |
Form | Liquid |
Purity | ˃ 95% as determined by SDS-PAGE |
Application Notes | |
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Application | WB, ICC, IF |
Application Notes | WB: 1:1000-1:10000 The optimal working dilutions should be determined by the end user. |
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