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This Mouse Monoclonal antibody is specific for Coxsackievirus CVB3 protein. The antibody can be used for applications: ELISA. The antibody is for Hand, Foot, and Mouth disease (HFMD) disease research use only and is not approved for use in humans or in clinical diagnosis.
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|Product Catetory||Primary Antibody|
|Species Reactivity||CVB1, CVB3, CVB6|
|Specificity||CVB1, CVB3, CVB6|
|Immunogen||Coxsackievirus B3 (CVB3)|
|Full Name||Coxsackievirus B3|
|Introduction||Coxsackieviruses, the leading causes of aseptic meningitis, are a few related enteroviruses that belong to the Picornaviridae family of non-enveloped, linear, positive-sense single-stranded RNA viruses. Coxsackieviruses are divided into group A and group B viruses based on early observations of their pathogenicity in neonatal mice. Group A coxsackieviruses (CVA) were noted to cause a flaccid paralysis while group B coxsackieviruses (CVB) were noted to cause a spastic paralysis. At least 23 serotypes (1-22, 24) of CVA and six serotypes (1-6) of CVB are recognized.|
|Alternative Names||Coxsackievirus B3, CVB3, Group B coxsackieviruses, Group B coxsackieviruses 3|
|Related Disease||Hand, Foot, and Mouth disease (HFMD)|
|Virus Classification||Positive-sense RNA Virus|
|Packaging, Storage & Formulations|
|Purification||Chromatography on protein A Sepharose|
|Storage||Store at 4°C for short term. Store at -20°C for long term. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.|
|Preservative||0.09% sodium azide|
|Formulation||PBS, pH 7.4, 0.09 % sodium azide (NaN₃)|
|Purity||>95% as determined by SDS-PAGE|
|Application Notes||The optimal working dilutions should be determined by the end user.|