Lenti-SARS-CoV-2 S Pseudovirus [GFP, MLV Packaging System] (CAT#: PSV-001CQ)

Lenti-SARS-CoV-2 S Pseudovirus is produced by cotransfecting the retroviral packaging cell line GP2-293 with the pQCXIX vector expressing GFP and plasmids encoding the S-protein. Pseudovirus-containing supernatant was harvested 48 h following transfection. The supernatant was cleared of cell debris by centrifugation and filtered through a 0.45-μm-pore-size filter. The produced pseudoviruses carry SARS-CoV-2 S proteins, which is a powerful tool for SARS-CoV-2 vaccine and entry inhibitor research.

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Product Details
Virus Packaging ProteinS
Packaging SystemLentivirus
Packaging CellGP2-293
Reporter GeneGFP
Application NotesThe pseudovirus can be usd for the following applications:
1. Antibody neutralization assay, Serum neutralization assay.
2. As virus standard alternative in diagnostic assay or others.
3. Drug screening including vaccine development, viral entry inhibitor development.
4. As a safe virology tool to discover the virus entry mechanisms.
Titer>1^10 virus copies/mL
StorageStore at -80°C and stable for 1 year from the date of shipment, avoiding freeze/thaw cycles.
NoteThe pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus.
Pseudovirus Details
Virus FamilyCoronaviridae
Virus SpeciesSARS-CoV-2
Virus ClassificationPositive-sense RNA Virus
Related DiseaseCOVID-19
IntroductionAn outbreak of a novel coronavirus disease (COVID-19; previously known as 2019-nCoV) was reported since last December, 2019. Now COVID-19 is an emerging, rapidly evolving situation, and has become a pandemic.SARS-CoV-2 consists of four structural proteins, including S (spike), E (envelope), M (membrane), and N (nucleocapsid) proteins. As an important envelope protein, S protein is identified as the protein responsible for virus entry into human cells, and S protein is the major target for anti-SARS-CoV-2 therapeutics discovery.
Alternative NamesSARS-CoV-2, 2019nCoV, COVID-19, S, Spike, Pseudovirus, Spike Pseudovirus, S Pseudovirus, SARS-CoV-2 Spike Pseudovirus, SARS-CoV-2 S Pseudovirus, COVID-19 Spike Pseudovirus, COVID-19 S Pseudovirus
Gene ID43740568
All products and services are intended for Research Use Only, and NOT to be used in diagnostic or therapeutic procedures.

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