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Cat#: VRS-0124-YT5248
Lenti-LASV GP Pseudovirus [HIV-1 Packaging System]
LASV GPC Pseudovirus is produced by cotransfecting HEK293T cells with LASV GPC plasmids and pSG3Δenv encoding envelope-deficient core of HIV-1. Pseudovirus-containing supernatant was harvested 72 h following transfection. The supernatant was cleared of cell debris by centrifugation and filtered through a 0.45-μm-pore-size filter. The produced pseudoviruses carry LASV GPC proteins, which is a powerful tool for LASV vaccine and entry inhibitor research.
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- Product Summary
- Packaging, Storage & Formulations
- Target Details
Product Summary
| Type : | Pseudovirus |
| Virus Name : | Lassa Virus |
| Virus Packaging Protein : | GPC |
| Packaging System : | HIV-1 Packaging System |
| Packaging Cell : | 293T |
| Titer : | >1x 108 virus copies/mL |
| Application Notes : | The pseudovirus can be usd for the following applications: 1. Antibody neutralization assay, Serum neutralization assay. 2. As virus standard alternative in diagnostic assay or others. 3. Drug screening including vaccine development, viral entry inhibitor development. 4. As a safe virology tool to discover the virus entry mechanisms. |
Packaging, Storage & Formulations
| Form : | Liquid |
| Storage : | Store at -80°C and stable for 6 months from the date of shipment, avoiding freeze/thaw cycles. |
| Shipping : | Dry ice |
| Note : | The pseudovirus can be used under BSL-2 conditions. Please reach out to our scientists for detailed instructions or guidelines of the pseudovirus. |
Target Details
| Introduction : | Lassa virus (LASA) is a single-stranded RNA virus belonging to the family of Arenaviridae. It is a biosafety level 4 Old World arenavirus that causes haemorrhagic fever in West Africa. The LASV membrane glycoprotein is processed into GP1 and GP2 and an unusual stable signal peptide (SSP). GP1 is responsible for receptor binding. GP2 belongs to the class I fusion protein family and is involved in mediating fusion of the virion with a cell membrane. SSP is responsible for proper processing of GPC. |
| Alternative Names : | GPC; LASV GPC; LASVsSgp2; LASV glycoprotein precursor; GP1; GP2 |
| Gene ID : | 956585 |
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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