Human Anti-SARS-CoV-2 S RBD Monoclonal Antibody (XF0050) (CAT#: VRX-0104F)

This human Monoclonal antibody (XF0050) is a human IgG1 antiobdy specific for SARS-CoV-2 S RBD domain. It can inhibit or neutralize the interaction between SARS-CoV-2 spike protein RBD domain and ACE2. The antibody can be used for applications: WB, ELISA, Neut. The antibody is for research use only and is not approved for use in humans or in clinical diagnosis.

Specific Inquiry
  • Size:

(Note: Please select the requirements to fit you project. If you have any other requirements, please specify. If no specific requirements, you don't need to select any button.)

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number

Product Summary
Product CategoryPrimary antibody
Species ReactivitySARS-CoV-2
ApplicationWB, ELISA, Neut
Product Details
SpecificityThis human IgG1 antibody recognizes the SARS-CoV-2 spike protein RBD domain and can inhibit or neutralize the interaction between S RBD and ACE2. The reactivity with other coronavirus hasn't been tested.
AffinityIC50=1.47 μg/ml
IsotypeIgG1, kappa
Expression system293
Antigen Details
Full NameSpike glycoprotein
IntroductionThe spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.
Gene ID43740568
Alternative NamesS, S glycoprotein, Spike, Spike glycoprotein, Surface glycoprotein, SARS-CoV-2, SARS-CoV-2 S, SARS-CoV-2 Spike, SARS-CoV-2 Surface glycoprotein, 2019-nCoV, 2019-nCoV S, 2019-nCoV Spike, 2019-nCoV Surface glycoprotein, COVID-19, COVID-19 S, COVID-19 Spike, COVID-19 Surface glycoprotein
Related DiseaseCOVID-19
Virus Details
Virus FamilyCoronaviridae
Virus SpeciesSARS-CoV-2
Virus ClassificationPositive-sense RNA Virus
Packaging, Storage & Formulations
StorageStore at 4°C for short term (12 months in lyophilized state). Store at -20°C for long term (-80°C for 3 years under sterile conditions after reconstitution. Avoid repeated freeze/thaw cycles. Refer to the COA file for specifics.
BufferPBS (pH 7.4)
FormulationLyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally trehalose is added as protectant before lyophilization.
Purity> 95% as determined by SDS
Application Notes
ApplicationWB, ELISA, Neut
Application NotesThe optimal working dilutions should be determined by the end user.
All products and services are intended for Research Use Only, and NOT to be used in diagnostic or therapeutic procedures.
Related products


3D IHC3D Immunohistochemistry
ActivActivation Assay
ALPHAAmplified Luminescent Proximity Homogeneous Assay
ADCCAntibody-dependent Cellular Cytotoxicity Assay
ApopApoptosis Assay
CACell-based Assay/Cellular Assay
ChIPChromatin Immunoprecipitation
CMCDComplement Mediated Cell Depletion
CDCComplement-dependent Cytotoxicity Assay
CostimCostimulation Assay
CytCytotoxicity Assay
DepDepletion Assay
DBDot Blot/Slot blot
EMElectron Microscopy
EMSAElectrophoretic Mobility Shift Assay
ELISAEnzyme-Linked Immunosorbent Assay
ELISpotEnzyme-linked Immunosorbent Spot
FCFlow Cytometry
FIAFluorescence Immunoassay
FRETFluorescence Resonance Energy Transfer Microscopy
FuncSFunctional Assay
GSGel Super Shift Assay
HAHemagglutination Assay
REImmunohistology-Resin Sections
IRMAImmunoradiometric Assay
ISHIn Situ Hybridization
InhibInhibition Assay
ICFCIntracellular Staining for Flow Cytometry
Live-cell imagingLive-cell Imaging Assay
CyTOFMass Cytometry
MeDIPMethylated DNA Immunoprecipitation
MAMicroagglutination Assay
NeutNeutralization Assay
PAPeptide Array
PPProtein Purification
RIRadial Immunodiffusion
StimStimulation Assay
SPRSurface Plasmon Resonance
TCAT-Cell Activation Assay
TRFTime-Resolved Fluorescence
TCTissue Culture
WBWestern Blot
HIHemagglutinin Inhibition
FLISAFluorescence-linked immunosorbent assay
Dual ISH-IHCDual In Situ Hybridization-Immunohistochemistry
ICFCIntracellular Staining for Flow Cytometry
KDKnockdown Validated
BLIBio-Layer Interferometry
LFIALateral-Flow Immunochromatographic Assay
LFALateral flow assay

Be the first to learn more about exclusive virology antibody products, services and latest updates.


Copyright © 2023 Creative Biolabs. All Rights Reserved.

Inquiry Basket