Human Anti-SARS-CoV-2 S, IgA, lambda, Monoclonal Antibody (XX0408)

Datasheet

MSDS

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Lot Number

Product Summary
Product Catetory	Primary Antibody
Target	S
Host	Human
Species Reactivity	SARS-CoV-2
Clonality	Monoclonal
Application	ELISA, FC, Neut, FuncS

Product Summary

Product Catetory

Primary Antibody

Target

Host

Human

Species Reactivity

SARS-CoV-2

Clonality

Monoclonal

Application

ELISA, FC, Neut, FuncS

Product Details
Specificity	This antibody reacts with S of SARS-CoV-2.
Clone	XX0408
Immunogen	SARS-CoV-2
Isotype	IgA, lambda
Conjugation	Unconjugated

Product Details

Specificity

This antibody reacts with S of SARS-CoV-2.

Clone

XX0408

Immunogen

SARS-CoV-2

Isotype

IgA, lambda

Conjugation

Unconjugated

Antigen Details
Full Name	Spike glycoprotein
Introduction	The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.
Gene ID	43740568
UniProt ID	P0DTC2
Alternative Names	S-protein; SARS-CoV2; SARS Coronavirus 2; SARS-CoV-2; SARS CoV 2; 2019-nCoV; Severe acute respiratory syndrome coronavirus 2; Spike protein; S protein; SARS-CoV 2 S protein; S glycoprotein; E2; Peplomer protein; SARS-CoV2
Related Disease	COVID-19

Antigen Details

Full Name

Spike glycoprotein

Introduction

The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity. The main functions for the Spike protein are summarized as: Mediate receptor binding and membrane fusion; Defines the range of the hosts and specificity of the virus; Main component to bind with the neutralizing antibody; Key target for vaccine design; Can be transmitted between different hosts through gene recombination or mutation of the receptor binding domain (RBD), leading to a higher mortality rate.

Gene ID

43740568

UniProt ID

P0DTC2

Alternative Names

S-protein; SARS-CoV2; SARS Coronavirus 2; SARS-CoV-2; SARS CoV 2; 2019-nCoV; Severe acute respiratory syndrome coronavirus 2; Spike protein; S protein; SARS-CoV 2 S protein; S glycoprotein; E2; Peplomer protein; SARS-CoV2

Related Disease

COVID-19

Virus Details
Virus Family	Coronaviridae
Virus Species	SARS-CoV-2
Virus Classification	Positive-sense RNA Virus

Virus Details

Virus Family

Coronaviridae

Virus Species

SARS-CoV-2

Virus Classification

Positive-sense RNA Virus

Packaging, Storage & Formulations
Purification	Affinity Purified using a recombinant lectin column
Storage	This antibody should be stored at 4°C for short term without detectable loss of activity. For long term, antibody products should be stored at -20°C or below. Avoid multiple freeze-thaw cycles.
Buffer	PBS
Form	Liquid
Formulation	PBS, 0.02% Proclin 300
Concentration	1.0 mg/mL
Purity	> 95 % as determined by SDS-PAGE and SEC-HPLC.

Packaging, Storage & Formulations

Purification

Affinity Purified using a recombinant lectin column

Storage

This antibody should be stored at 4°C for short term without detectable loss of activity. For long term, antibody products should be stored at -20°C or below. Avoid multiple freeze-thaw cycles.

Buffer

PBS

Form

Liquid

Formulation

PBS, 0.02% Proclin 300

Concentration

1.0 mg/mL

Purity

> 95 % as determined by SDS-PAGE and SEC-HPLC.

Application Notes
Application	ELISA, FC, Neut, FuncS
Application Notes	The optimal working dilutions should be determined by the end user.

Application Notes

Application

ELISA, FC, Neut, FuncS

Application Notes

The optimal working dilutions should be determined by the end user.

Human Anti-SARS-CoV-2 S, IgA, lambda, Monoclonal Antibody (XX0408)

Human Anti-SARS-CoV-2 S, IgA, lambda, Monoclonal Antibody (XX0408) (CAT#: VRX-1943X)

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